Enrichment results for BIOCARTA


Cancer-typePathwayQ-valueP-valuePathway sizeCancer set sizeDPDNGPGN
parson_gbmh_igf1rPathway:Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation1.54e-067.9e-092094787208920
parson_gbmh_badPathway:Regulation of BAD phosphorylation9.22e-069.46e-081794688178923
parson_gbmh_vdrPathway:Control of Gene Expression by Vitamin D Receptor3.41e-055.25e-072494688248916
parson_gbmh_eif4Pathway:Regulation of eIF4e and p70 S6 Kinase0.0002414.94e-062094589208920
parson_gbmh_mTORPathway:mTOR Signaling Pathway0.0002887.38e-062294589228918
parson_gbmh_egfPathway:EGF Signaling Pathway0.0005061.77e-052794589278913
parson_gbmh_rbPathway:RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage0.0005061.82e-051294490128928
parson_gbmh_hSWI-SNFpathway:Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes0.001516.97e-051894490188922
parson_gbmh_ptenPathway:PTEN dependent cell cycle arrest and apoptosis0.001516.97e-051894490188922
parson_gbmh_chemicalPathway:Apoptotic Signaling in Response to DNA Damage0.001629.96e-052094490208920
parson_gbmh_crebPathway:Transcription factor CREB and its extracellular signals0.001629.96e-052094490208920
parson_gbmh_igf1mtorpathway:Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway0.001629.96e-052094490208920
parson_gbmh_aktPathway:AKT Signaling Pathway0.001640.0001182194490218919
parson_gbmh_rac1Pathway:Rac 1 cell motility signaling pathway0.001640.0001182194490218919
parson_gbmh_carm-erPathway:CARM1 and Regulation of the Estrogen Receptor0.001790.0001382294490228918
parson_gbmh_g2Pathway:Cell Cycle: G2/M Checkpoint0.001840.0001612394490238917
parson_gbmh_nuclearRsPathway:Nuclear Receptors in Lipid Metabolism and Toxicity0.001840.0001612394490238917
parson_gbmh_agrPathway:Agrin in Postsynaptic Differentiation0.002970.0002792794490278913
parson_gbmh_btg2Pathway:BTG family proteins and cell cycle regulation0.002970.0002891094391108930
parson_gbmh_cblPathway:CBL mediated ligand-induced downregulation of EGF receptors0.003390.0003651194391118929
parson_gbmh_egfr_smrtePathway:Map Kinase Inactivation of SMRT Corepressor0.003390.0003651194391118929
parson_gbmh_hesPathway:Segmentation Clock0.004020.0004531294391128928
parson_gbmh_LairPathway:Cells and Molecules involved in local acute inflammatory response0.004320.0005541394391138927
parson_gbmh_erythPathway:Erythrocyte Differentiation Pathway0.004320.0005541394391138927
parson_gbmh_trkaPathway:Trka Receptor Signaling Pathway0.004320.0005541394391138927
parson_gbmh_integrinPathway:Integrin Signaling Pathway0.004640.0006193494490348906
parson_gbmh_il2rbPathway:IL-2 Receptor Beta Chain in T cell Activation0.005450.0007543694490368904
parson_gbmh_mCalpainPathway:mCalpain and friends in Cell motility0.00630.0009371694391168924
parson_gbmh_no1Pathway:Actions of Nitric Oxide in the Heart0.00630.0009371694391168924
parson_gbmh_cardiacegfPathway:Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy0.006670.001091794391178923
parson_gbmh_pmlPathway:Regulation of transcriptional activity by PML0.006670.001091794391178923
parson_gbmh_spryPathway:Sprouty regulation of tyrosine kinase signals0.006670.001091794391178923
parson_gbmh_atrbrcaPathway:Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility0.007480.001271894391188922
parson_gbmh_ptdinsPathway:Phosphoinositides and their downstream targets.0.008350.001461994391198921
parson_gbmh_igf1Pathway:IGF-1 Signaling Pathway0.009930.001882194391218919
parson_gbmh_rhoPathway:Rho cell motility signaling pathway0.009930.001882194391218919
parson_gbmh_telPathway:Telomeres, Telomerase, Cellular Aging, and Immortality0.009930.001882194391218919
parson_gbmh_mapkPathway:MAPKinase Signaling Pathway0.01010.001968194589818859
parson_gbmh_rasPathway:Ras Signaling Pathway0.01060.002132294391228918
parson_gbmh_her2Pathway:Role of ERBB2 in Signal Transduction and Oncology0.01130.002382394391238917
parson_gbmh_tffPathway:Trefoil Factors Initiate Mucosal Healing0.01130.002382394391238917
parson_gbmh_RacCycDPathway:Influence of Ras and Rho proteins on G1 to S Transition0.01450.003282694391268914
parson_gbmh_g1Pathway:Cell Cycle: G1/S Check Point 0.01450.003282694391268914
parson_gbmh_gsk3Pathway:Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages0.01450.003282694391268914
parson_gbmh_tnfr1Pathway:TNFR1 Signaling Pathway0.01570.003612794391278913
parson_gbmh_fasPathway:FAS signaling pathway ( CD95 )0.01680.003972894391288912
parson_gbmh_erkPathway:Erk1/Erk2 Mapk Signaling pathway0.02140.005173194391318909
parson_gbmh_cell2cellPathway:Cell to Cell Adhesion Signaling0.02580.00661094292108930
parson_gbmh_mta3Pathway:Downregulated of MTA-3 in ER-negative Breast Tumors0.02580.00661094292108930
parson_gbmh_skp2e2fPathway:E2F1 Destruction Pathway0.02580.00661094292108930
parson_gbmh_pparaPathway:Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha)0.02700.007073594391358905
parson_gbmh_nfatPathway:NFAT and Hypertrophy of the heart (Transcription in the broken heart)0.02750.00763694391368904
parson_gbmh_bArrestinPathway:?-arrestins in GPCR Desensitization0.02750.007751194292118929
parson_gbmh_pgc1aPathway:Regulation of PGC-1a0.02750.007751194292118929
parson_gbmh_ranbp2Pathway:Sumoylation by RanBP2 Regulates Transcriptional Repression0.02750.007751194292118929
parson_gbmh_arfPathway:Tumor Suppressor Arf Inhibits Ribosomal Biogenesis0.02970.008991294292128928
parson_gbmh_compPathway:Complement Pathway0.02970.008991294292128928
parson_gbmh_eicosanoidPathway:Eicosanoid Metabolism0.02970.008991294292128928
parson_gbmh_lympathway:Adhesion and Diapedesis of Lymphocytes0.02970.008991294292128928
parson_gbmh_ck1Pathway:Regulation of ck1/cdk5 by type 1 glutamate receptors0.03290.01031394292138927
parson_gbmh_p27Pathway:Regulation of p27 Phosphorylation during Cell Cycle Progression0.03290.01031394292138927
parson_gbmh_achPathway:Role of nicotinic acetylcholine receptors in the regulation of apoptosis0.03560.01171494292148926
parson_gbmh_ps1Pathway:Presenilin action in Notch and Wnt signaling0.03560.01171494292148926
parson_gbmh_stemPathway:Regulation of hematopoiesis by cytokines0.03560.01171494292148926
parson_gbmh_il3Pathway:IL 3 signaling pathway0.03890.01321594292158925
parson_gbmh_nkcellsPathway:Ras-Independent pathway in NK cell-mediated cytotoxicity0.03890.01321594292158925
parson_gbmh_intrinsicPathway:Intrinsic Prothrombin Activation Pathway0.04160.01471694292168924
parson_gbmh_p53Pathway:p53 Signaling Pathway0.04160.01471694292168924
parson_gbmh_tidPathway:Chaperones modulate interferon Signaling Pathway0.04160.01471694292168924
parson_gbmh_hdacPathway:Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK)0.04550.01631794292178923
parson_gbmh_HivnefPathway:HIV-I Nef: negative effector of Fas and TNF0.04820.01765094391508890
parson_gbmh_CSKPathway:Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor0.05140.01981994292198921
parson_gbmh_atmPathway:ATM Signaling Pathway0.05140.01981994292198921
parson_gbmh_ctcfPathway:CTCF: First Multivalent Nuclear Factor0.05140.01981994292198921
parson_gbmh_ctla4Pathway:The Co-Stimulatory Signal During T-cell Activation0.05140.01981994292198921
parson_gbmh_edg1Pathway:Phospholipids as signalling intermediaries0.05470.02162094292208920
parson_gbmh_epoPathway:EPO Signaling Pathway0.05470.02162094292208920
parson_gbmh_gleevecpathway:Inhibition of Cellular Proliferation by Gleevec0.05880.02352194292218919
parson_gbmh_ecmPathway:Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia0.06210.02552294292228918
parson_gbmh_insulinPathway:Insulin Signaling Pathway0.06210.02552294292228918
parson_gbmh_cxcr4Pathway:CXCR4 Signaling Pathway0.06540.02752394292238917
parson_gbmh_p53hypoxiaPathway:Hypoxia and p53 in the Cardiovascular system0.06540.02752394292238917
parson_gbmh_pdgfPathway:PDGF Signaling Pathway0.07460.03182594292258915
parson_gbmh_ghPathway:Growth Hormone Signaling Pathway0.07890.0342694292268914
parson_gbmh_bcrPathway:BCR Signaling Pathway0.08850.03862894292288912
parson_gbmh_At1rPathway:Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling0.09290.0412994292298911
parson_gbmh_alkPathway:ALK in cardiac myocytes0.1060.04853294292328908
parson_gbmh_biopeptidesPathway:Bioactive Peptide Induced Signaling Pathway0.1060.04853294292328908
parson_gbmh_fcer1Pathway:Fc Epsilon Receptor I Signaling in Mast Cells0.1060.04853294292328908
parson_gbmh_metPathway:Signaling of Hepatocyte Growth Factor Receptor0.1220.05643594292358905
parson_gbmh_keratinocytePathway:Keratinocyte Differentiation0.1510.07054094292408900
parson_gbmh_eosinophilsPathway:The Role of Eosinophils in the Chemokine Network of Allergy0.2080.099499419398931
parson_gbmh_ranMSpathway:Role of Ran in mitotic spindle regulation0.2080.099499419398931
parson_gbmh_GATA3pathway:GATA3 participate in activating the Th2 cytokine genes expression0.2120.1091094193108930
parson_gbmh_HBxPathway:Calcium Signaling by HBx of Hepatitis B virus0.2120.1091094193108930
parson_gbmh_Lis1Pathway:Lissencephaly gene (LIS1) in neuronal migration and development0.2120.1091094193108930
parson_gbmh_eradPathway:ER?associated degradation (ERAD) Pathway0.2120.1091094193108930
parson_gbmh_glycolysisPathway:Glycolysis Pathway0.2120.1091094193108930
parson_gbmh_mef2dPathway:Role of MEF2D in T-cell Apoptosis0.2120.1091094193108930
parson_gbmh_monocytePathway:Monocyte and its Surface Molecules0.2120.1091094193108930
parson_gbmh_eponfkbPathway:Erythropoietin mediated neuroprotection through NF-kB0.2190.1181194193118929
parson_gbmh_extrinsicPathway:Extrinsic Prothrombin Activation Pathway0.2190.1181194193118929
parson_gbmh_fibrinolysisPathway:Fibrinolysis Pathway0.2190.1181194193118929
parson_gbmh_il4Pathway:IL 4 signaling pathway0.2190.1181194193118929
parson_gbmh_prionPathway:Prion Pathway0.2190.1181194193118929
parson_gbmh_akapCentrosomePathway:Protein Kinase A at the Centrosome0.2230.1271294193128928
parson_gbmh_d4gdiPathway:D4-GDI Signaling Pathway0.2230.1271294193128928
parson_gbmh_myosinPathway:PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase0.2230.1271294193128928
parson_gbmh_prc2Pathway:The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails0.2230.1271294193128928
parson_gbmh_ranklPathway:Bone Remodelling0.2230.1271294193128928
parson_gbmh_ucalpainPathway:uCalpain and friends in Cell spread0.2230.1271294193128928
parson_gbmh_cdk5Pathway:Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway0.2370.1361394193138927
parson_gbmh_amiPathway:Acute Myocardial Infarction0.2380.1451494193148926
parson_gbmh_barr-mapkPathway:Role of ?-arrestins in the activation and targeting of MAP kinases0.2380.1451494193148926
parson_gbmh_ghrelinPathway:Ghrelin: Regulation of Food Intake and Energy Homeostasis0.2380.1451494193148926
parson_gbmh_hcmvPathway:Human Cytomegalovirus and Map Kinase Pathways0.2380.1451494193148926
parson_gbmh_longevityPathway:The IGF-1 Receptor and Longevity0.2380.1451494193148926
parson_gbmh_rarrxrPathway:Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells0.2380.1451494193148926
parson_gbmh_vipPathway:Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells0.2380.1451494193148926
parson_gbmh_PDZsPathway:Synaptic Proteins at the Synaptic Junction0.2390.1541594193158925
parson_gbmh_arapPathway:ADP-Ribosylation Factor0.2390.1541594193158925
parson_gbmh_arenrf2Pathway:Oxidative Stress Induced Gene Expression Via Nrf20.2390.1541594193158925
parson_gbmh_hifPathway:Hypoxia-Inducible Factor in the Cardiovascular System0.2390.1541594193158925
parson_gbmh_il17Pathway:IL 17 Signaling Pathway0.2390.1541594193158925
parson_gbmh_pitx2Pathway:Multi-step Regulation of Transcription by Pitx20.2390.1541594193158925
parson_gbmh_smPathway:Spliceosomal Assembly0.2390.1541594193158925
parson_gbmh_Par1Pathway:Thrombin signaling and protease-activated receptors0.2480.1631694193168924
parson_gbmh_etsPathway:METS affect on Macrophage Differentiation0.2480.1631694193168924
parson_gbmh_cytokinePathway:Cytokine Network0.2580.1721794193178923
parson_gbmh_vegfPathway:VEGF, Hypoxia, and Angiogenesis0.2580.1721794193178923
parson_gbmh_ngfPathway:Nerve growth factor pathway (NGF)0.2690.1801894193188922
parson_gbmh_mitochondriaPathway:Role of Mitochondria in Apoptotic Signaling0.2790.1891994193198921
parson_gbmh_bArrestin-srcPathway:Roles of ?-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling0.2870.1972094193208920
parson_gbmh_dcPathway:Dendritic cells in regulating TH1 and TH2 Development0.2870.1972094193208920
parson_gbmh_TPOPathway:TPO Signaling Pathway0.2890.2062194193218919
parson_gbmh_caspasePathway:Caspase Cascade in Apoptosis0.2890.2062194193218919
parson_gbmh_ceramidePathway:Ceramide Signaling Pathway0.2890.2062194193218919
parson_gbmh_il6Pathway:IL 6 signaling pathway0.2890.2062194193218919
parson_gbmh_mPRPathway:How Progesterone Initiates the Oocyte Maturation0.2890.2062194193218919
parson_gbmh_cellcyclePathway:Cyclins and Cell Cycle Regulation0.2980.2142294193228918
parson_gbmh_gpcrPathway:Signaling Pathway from G-Protein Families0.3030.2222394193238917
parson_gbmh_il2Pathway:IL 2 signaling pathway0.3030.2222394193238917
parson_gbmh_inflamPathway:Cytokines and Inflammatory Response0.3030.2222394193238917
parson_gbmh_pyk2Pathway:Links between Pyk2 and Map Kinases0.3440.2542794193278913
parson_gbmh_tollPathway:Toll-Like Receptor Pathway0.3830.2853194193318909
parson_gbmh_p38mapkPathway:p38 MAPK Signaling Pathway 0.410.3073494193348906
parson_gbmh_tcrPathway:T Cell Receptor Signaling Pathway0.4260.3213694193368904
parson_gbmh_41bbPathway:The 4-1BB-dependent immune response111794094178923
parson_gbmh_CCR3Pathway:CCR3 signaling in Eosinophils112394094238917
parson_gbmh_Ccr5Pathway:Pertussis toxin-insensitive CCR5 Signaling in Macrophage111294094128928
parson_gbmh_IL12Pathway:IL12 and Stat4 Dependent Signaling Pathway in Th1 Development112094094208920
parson_gbmh_RELAPathway:Acetylation and Deacetylation of RelA in The Nucleus111394094138927
parson_gbmh_actinYPathway:Y branching of actin filaments111194094118929
parson_gbmh_akap95Pathway:AKAP95 role in mitosis and chromosome dynamics1199409498931
parson_gbmh_asbcellPathway:Antigen Dependent B Cell Activation111394094138927
parson_gbmh_bbcellPathway:Bystander B Cell Activation1199409498931
parson_gbmh_bcellsurvivalPathway:B Cell Survival Pathway111394094138927
parson_gbmh_blymphocytePathway:B Lymphocyte Cell Surface Molecules111194094118929
parson_gbmh_calcineurinPathway:Effects of calcineurin in Keratinocyte Differentiation111094094108930
parson_gbmh_cd40Pathway:CD40L Signaling Pathway111494094148926
parson_gbmh_cdMacPathway:Cadmium induces DNA synthesis and proliferation in macrophages111594094158925
parson_gbmh_ctlPathway:CTL mediated immune response against target cells 111394094138927
parson_gbmh_deathPathway:Induction of apoptosis through DR3 and DR4/5 Death Receptors 112594094258915
parson_gbmh_eif2Pathway:Regulation of eIF2111194094118929
parson_gbmh_erk5Pathway:Role of Erk5 in Neuronal Survival111594094158925
parson_gbmh_fMLPpathway:fMLP induced chemokine gene expression in HMC-1 cells112694094268914
parson_gbmh_gcrPathway:Corticosteroids and cardioprotection111494094148926
parson_gbmh_granulocytesPathway:Adhesion and Diapedesis of Granulocytes111394094138927
parson_gbmh_hsp27Pathway:Stress Induction of HSP Regulation111394094138927
parson_gbmh_il1rPathway:Signal transduction through IL1R112594094258915
parson_gbmh_il5Pathway:IL 5 Signaling Pathway111194094118929
parson_gbmh_il7Pathway:IL-7 Signal Transduction111494094148926
parson_gbmh_malPathway:Role of MAL in Rho-Mediated Activation of SRF111994094198921
parson_gbmh_mhcPathway:Antigen Processing and Presentation1179409478933
parson_gbmh_nfkbPathway:NF-kB Signaling Pathway112194094218919
parson_gbmh_nktPathway:Selective expression of chemokine receptors during T-cell polarization112394094238917
parson_gbmh_no2il12Pathway:NO2-dependent IL 12 Pathway in NK cells111194094118929
parson_gbmh_nthiPathway:NFkB activation by Nontypeable Hemophilus influenzae112394094238917
parson_gbmh_rabPathway:Rab GTPases Mark Targets In The Endocytotic Machinery111294094128928
parson_gbmh_reckPathway:Inhibition of Matrix Metalloproteinases111194094118929
parson_gbmh_setPathway:Granzyme A mediated Apoptosis Pathway111194094118929
parson_gbmh_shhPathway:Sonic Hedgehog (Shh) Pathway111094094108930
parson_gbmh_sppaPathway:Aspirin Blocks Signaling Pathway Involved in Platelet Activation112094094208920
parson_gbmh_stathminPathway:Stathmin and breast cancer resistance to antimicrotubule agents111294094128928
parson_gbmh_stressPathway:TNF/Stress Related Signaling112394094238917
parson_gbmh_tall1Pathway:TACI and BCMA stimulation of B cell immune responses.111494094148926
parson_gbmh_tcapoptosisPathway:HIV Induced T Cell Apoptosis111094094108930
parson_gbmh_tcraPathway:Lck and Fyn tyrosine kinases in initiation of TCR Activation111394094138927
parson_gbmh_tcytotoxicPathway:T Cytotoxic Cell Surface Molecules111394094138927
parson_gbmh_tgfbPathway:TGF beta signaling pathway111694094168924
parson_gbmh_th1th2Pathway:Th1/Th2 Differentiation112194094218919
parson_gbmh_thelperPathway:T Helper Cell Surface Molecules111294094128928
parson_gbmh_tnfr2Pathway:TNFR2 Signaling Pathway111694094168924
parson_gbmh_tob1Pathway:Role of Tob in T-cell activation111594094158925
parson_gbmh_wntPathway:WNT Signaling Pathway112494094248916