Pathway Enlargement Enrichment results for BIOCARTA


Cancer-typePathwayQ-valueP-valuePathway sizeCancer set sizeDPDNGPGN
parson_gbmh_vdrPathway:Control of Gene Expression by Vitamin D Receptor4.18e-052.36e-07281167109288912
parson_gbmh_igf1rPathway:Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation4.18e-054.29e-07311167109318909
parson_gbmh_badPathway:Regulation of BAD phosphorylation9.42e-051.45e-06231166110238917
parson_gbmh_her2Pathway:Role of ERBB2 in Signal Transduction and Oncology0.0001813.92e-06451167109458895
parson_gbmh_carm-erPathway:CARM1 and Regulation of the Estrogen Receptor0.0001814.65e-06291166110298911
parson_gbmh_hSWI-SNFpathway:Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes0.0005271.68e-05211165111218919
parson_gbmh_aktPathway:AKT Signaling Pathway0.0005272.04e-05221165111228918
parson_gbmh_mapkPathway:MAPKinase Signaling Pathway0.0005272.16e-0511111691071118829
parson_gbmh_mTORPathway:mTOR Signaling Pathway0.0006362.94e-05241165111248916
parson_gbmh_rbPathway:RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage0.0008054.13e-05121164112128928
parson_gbmh_eif4Pathway:Regulation of eIF4e and p70 S6 Kinase0.001769.94e-05321165111328908
parson_gbmh_egfPathway:EGF Signaling Pathway0.001840.000113331165111338907
parson_gbmh_no1Pathway:Actions of Nitric Oxide in the Heart0.001940.000129171164112178923
parson_gbmh_igf1mtorpathway:Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway0.004280.000307221164112228918
parson_gbmh_nuclearRsPathway:Nuclear Receptors in Lipid Metabolism and Toxicity0.004640.000357231164112238917
parson_gbmh_g2Pathway:Cell Cycle: G2/M Checkpoint0.004730.000413241164112248916
parson_gbmh_rac1Pathway:Rac 1 cell motility signaling pathway0.004730.000413241164112248916
parson_gbmh_btg2Pathway:BTG family proteins and cell cycle regulation0.005780.000533101163113108930
parson_gbmh_chemicalPathway:Apoptotic Signaling in Response to DNA Damage0.006320.000616271164112278913
parson_gbmh_egfr_smrtePathway:Map Kinase Inactivation of SMRT Corepressor0.006470.000672111163113118929
parson_gbmh_ptenPathway:PTEN dependent cell cycle arrest and apoptosis0.006470.000697281164112288912
parson_gbmh_ranbp2Pathway:Sumoylation by RanBP2 Regulates Transcriptional Repression0.007060.000833121163113128928
parson_gbmh_cblPathway:CBL mediated ligand-induced downregulation of EGF receptors0.007060.000833121163113128928
parson_gbmh_LairPathway:Cells and Molecules involved in local acute inflammatory response0.007620.00102131163113138927
parson_gbmh_compPathway:Complement Pathway0.007620.00102131163113138927
parson_gbmh_erythPathway:Erythrocyte Differentiation Pathway0.007620.00102131163113138927
parson_gbmh_tnfr1Pathway:TNFR1 Signaling Pathway0.007920.00110321164112328908
parson_gbmh_hesPathway:Segmentation Clock0.008270.00122141163113148926
parson_gbmh_integrinPathway:Integrin Signaling Pathway0.008270.00123581165111588882
parson_gbmh_skp2e2fPathway:E2F1 Destruction Pathway0.009070.00145151163113158925
parson_gbmh_rasPathway:Ras Signaling Pathway0.009070.00149351164112358905
parson_gbmh_tollPathway:Toll-Like Receptor Pathway0.009070.00149351164112358905
parson_gbmh_fasPathway:FAS signaling pathway ( CD95 )0.009390.00164361164112368904
parson_gbmh_tffPathway:Trefoil Factors Initiate Mucosal Healing0.009390.00164361164112368904
parson_gbmh_crebPathway:Transcription factor CREB and its extracellular signals0.010.00180371164112378903
parson_gbmh_agrPathway:Agrin in Postsynaptic Differentiation0.01060.00197381164112388902
parson_gbmh_HivnefPathway:HIV-I Nef: negative effector of Fas and TNF0.01110.0021661165111668874
parson_gbmh_RacCycDPathway:Influence of Ras and Rho proteins on G1 to S Transition0.01300.00254411164112418899
parson_gbmh_tidPathway:Chaperones modulate interferon Signaling Pathway0.01320.00264191163113198921
parson_gbmh_pmlPathway:Regulation of transcriptional activity by PML0.01430.00301201163113208920
parson_gbmh_atrbrcaPathway:Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility0.01430.00301201163113208920
parson_gbmh_pparaPathway:Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha)0.01440.00322441164112448896
parson_gbmh_ptdinsPathway:Phosphoinositides and their downstream targets.0.01440.00341211163113218919
parson_gbmh_cardiacegfPathway:Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy0.01440.00341211163113218919
parson_gbmh_mCalpainPathway:mCalpain and friends in Cell motility0.01440.00341211163113218919
parson_gbmh_rhoPathway:Rho cell motility signaling pathway0.01440.00341211163113218919
parson_gbmh_il2rbPathway:IL-2 Receptor Beta Chain in T cell Activation0.01530.00374461164112468894
parson_gbmh_trkaPathway:Trka Receptor Signaling Pathway0.01530.00384221163113228918
parson_gbmh_vegfPathway:VEGF, Hypoxia, and Angiogenesis0.01530.00384221163113228918
parson_gbmh_spryPathway:Sprouty regulation of tyrosine kinase signals0.01870.00479241163113248916
parson_gbmh_igf1Pathway:IGF-1 Signaling Pathway0.0220.00587261163113268914
parson_gbmh_telPathway:Telomeres, Telomerase, Cellular Aging, and Immortality0.0220.00587261163113268914
parson_gbmh_atmPathway:ATM Signaling Pathway0.02380.00646271163113278913
parson_gbmh_gsk3Pathway:Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages0.02560.00709281163113288912
parson_gbmh_mta3Pathway:Downregulated of MTA-3 in ER-negative Breast Tumors0.0350.00987101162114108930
parson_gbmh_keratinocytePathway:Keratinocyte Differentiation0.03670.0105631164112638877
parson_gbmh_g1Pathway:Cell Cycle: G1/S Check Point 0.03680.0108331163113338907
parson_gbmh_pgc1aPathway:Regulation of PGC-1a0.03890.0116111162114118929
parson_gbmh_cell2cellPathway:Cell to Cell Adhesion Signaling0.04080.0134121162114128928
parson_gbmh_arfPathway:Tumor Suppressor Arf Inhibits Ribosomal Biogenesis0.04080.0134121162114128928
parson_gbmh_bArrestinPathway:?-arrestins in GPCR Desensitization0.04080.0134121162114128928
parson_gbmh_lympathway:Adhesion and Diapedesis of Lymphocytes0.04080.0134121162114128928
parson_gbmh_eicosanoidPathway:Eicosanoid Metabolism0.04080.0134121162114128928
parson_gbmh_cxcr4Pathway:CXCR4 Signaling Pathway0.04080.0134361163113368904
parson_gbmh_nthiPathway:NFkB activation by Nontypeable Hemophilus influenzae0.0460.0153381163113388902
parson_gbmh_eponfkbPathway:Erythropoietin mediated neuroprotection through NF-kB0.050.0174141162114148926
parson_gbmh_stemPathway:Regulation of hematopoiesis by cytokines0.050.0174141162114148926
parson_gbmh_erkPathway:Erk1/Erk2 Mapk Signaling pathway0.050.0174401163113408900
parson_gbmh_achPathway:Role of nicotinic acetylcholine receptors in the regulation of apoptosis0.05510.0195151162114158925
parson_gbmh_fcer1Pathway:Fc Epsilon Receptor I Signaling in Mast Cells0.05810.0209431163113438897
parson_gbmh_intrinsicPathway:Intrinsic Prothrombin Activation Pathway0.05820.0218161162114168924
parson_gbmh_ps1Pathway:Presenilin action in Notch and Wnt signaling0.05820.0218161162114168924
parson_gbmh_ck1Pathway:Regulation of ck1/cdk5 by type 1 glutamate receptors0.05820.0218161162114168924
parson_gbmh_alkPathway:ALK in cardiac myocytes0.05820.0221441163113448896
parson_gbmh_p27Pathway:Regulation of p27 Phosphorylation during Cell Cycle Progression0.06110.0241171162114178923
parson_gbmh_nkcellsPathway:Ras-Independent pathway in NK cell-mediated cytotoxicity0.06110.0241171162114178923
parson_gbmh_hdacPathway:Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK)0.06110.0241171162114178923
parson_gbmh_tcrPathway:T Cell Receptor Signaling Pathway0.06150.0246461163113468894
parson_gbmh_rarrxrPathway:Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells0.0640.0266181162114188922
parson_gbmh_p53Pathway:p53 Signaling Pathway0.0640.0266181162114188922
parson_gbmh_Par1Pathway:Thrombin signaling and protease-activated receptors0.0640.0266181162114188922
parson_gbmh_nfatPathway:NFAT and Hypertrophy of the heart (Transcription in the broken heart)0.06830.0287491163113498891
parson_gbmh_pitx2Pathway:Multi-step Regulation of Transcription by Pitx20.0730.0318201162114208920
parson_gbmh_ctla4Pathway:The Co-Stimulatory Signal During T-cell Activation0.0730.0318201162114208920
parson_gbmh_CSKPathway:Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor0.0730.0318201162114208920
parson_gbmh_il4Pathway:IL 4 signaling pathway0.07740.0345211162114218919
parson_gbmh_il3Pathway:IL 3 signaling pathway0.07740.0345211162114218919
parson_gbmh_ctcfPathway:CTCF: First Multivalent Nuclear Factor0.08930.0403231162114238917
parson_gbmh_epoPathway:EPO Signaling Pathway0.09480.0433241162114248916
parson_gbmh_tnfr2Pathway:TNFR2 Signaling Pathway0.1000.0464251162114258915
parson_gbmh_p53hypoxiaPathway:Hypoxia and p53 in the Cardiovascular system0.1060.0495261162114268914
parson_gbmh_RELAPathway:Acetylation and Deacetylation of RelA in The Nucleus0.1090.0528271162114278913
parson_gbmh_gleevecpathway:Inhibition of Cellular Proliferation by Gleevec0.1090.0528271162114278913
parson_gbmh_stressPathway:TNF/Stress Related Signaling0.1090.0528271162114278913
parson_gbmh_insulinPathway:Insulin Signaling Pathway0.1120.0561281162114288912
parson_gbmh_pdgfPathway:PDGF Signaling Pathway0.1120.0561281162114288912
parson_gbmh_ecmPathway:Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia0.1120.0561281162114288912
parson_gbmh_edg1Pathway:Phospholipids as signalling intermediaries0.1120.0561281162114288912
parson_gbmh_il2Pathway:IL 2 signaling pathway0.1140.0594291162114298911
parson_gbmh_nfkbPathway:NF-kB Signaling Pathway0.1140.0594291162114298911
parson_gbmh_caspasePathway:Caspase Cascade in Apoptosis0.1140.0594291162114298911
parson_gbmh_il1rPathway:Signal transduction through IL1R0.1140.0594291162114298911
parson_gbmh_ghPathway:Growth Hormone Signaling Pathway0.1250.0664311162114318909
parson_gbmh_gpcrPathway:Signaling Pathway from G-Protein Families0.1250.0664311162114318909
parson_gbmh_bcrPathway:BCR Signaling Pathway0.1650.0887371162114378903
parson_gbmh_At1rPathway:Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling0.1930.105411162114418899
parson_gbmh_ranMSpathway:Role of Ran in mitotic spindle regulation0.2180.1219116111598931
parson_gbmh_eosinophilsPathway:The Role of Eosinophils in the Chemokine Network of Allergy0.2180.1219116111598931
parson_gbmh_pyk2Pathway:Links between Pyk2 and Map Kinases0.2250.126461162114468894
parson_gbmh_mef2dPathway:Role of MEF2D in T-cell Apoptosis0.2320.132101161115108930
parson_gbmh_glycolysisPathway:Glycolysis Pathway0.2320.132101161115108930
parson_gbmh_extrinsicPathway:Extrinsic Prothrombin Activation Pathway0.2410.143111161115118929
parson_gbmh_monocytePathway:Monocyte and its Surface Molecules0.2410.143111161115118929
parson_gbmh_prionPathway:Prion Pathway0.2410.143111161115118929
parson_gbmh_GATA3pathway:GATA3 participate in activating the Th2 cytokine genes expression0.2410.143111161115118929
parson_gbmh_eradPathway:ER?associated degradation (ERAD) Pathway0.2410.143111161115118929
parson_gbmh_metPathway:Signaling of Hepatocyte Growth Factor Receptor0.2530.152521162114528888
parson_gbmh_akapCentrosomePathway:Protein Kinase A at the Centrosome0.2530.154121161115128928
parson_gbmh_Lis1Pathway:Lissencephaly gene (LIS1) in neuronal migration and development0.2530.154121161115128928
parson_gbmh_HBxPathway:Calcium Signaling by HBx of Hepatitis B virus0.260.165131161115138927
parson_gbmh_prc2Pathway:The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails0.260.165131161115138927
parson_gbmh_ranklPathway:Bone Remodelling0.260.165131161115138927
parson_gbmh_myosinPathway:PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase0.260.165131161115138927
parson_gbmh_biopeptidesPathway:Bioactive Peptide Induced Signaling Pathway0.260.165551162114558885
parson_gbmh_ucalpainPathway:uCalpain and friends in Cell spread0.2680.176141161115148926
parson_gbmh_d4gdiPathway:D4-GDI Signaling Pathway0.2680.176141161115148926
parson_gbmh_fibrinolysisPathway:Fibrinolysis Pathway0.2680.176141161115148926
parson_gbmh_vipPathway:Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells0.2680.176141161115148926
parson_gbmh_arapPathway:ADP-Ribosylation Factor0.280.187151161115158925
parson_gbmh_ghrelinPathway:Ghrelin: Regulation of Food Intake and Energy Homeostasis0.280.187151161115158925
parson_gbmh_smPathway:Spliceosomal Assembly0.2850.197161161115168924
parson_gbmh_amiPathway:Acute Myocardial Infarction0.2850.197161161115168924
parson_gbmh_longevityPathway:The IGF-1 Receptor and Longevity0.2850.197161161115168924
parson_gbmh_hifPathway:Hypoxia-Inducible Factor in the Cardiovascular System0.2850.197161161115168924
parson_gbmh_il17Pathway:IL 17 Signaling Pathway0.2850.197161161115168924
parson_gbmh_cd40Pathway:CD40L Signaling Pathway0.2930.207171161115178923
parson_gbmh_PDZsPathway:Synaptic Proteins at the Synaptic Junction0.2930.207171161115178923
parson_gbmh_arenrf2Pathway:Oxidative Stress Induced Gene Expression Via Nrf20.2930.207171161115178923
parson_gbmh_il7Pathway:IL-7 Signal Transduction0.2970.217181161115188922
parson_gbmh_hcmvPathway:Human Cytomegalovirus and Map Kinase Pathways0.2970.217181161115188922
parson_gbmh_tall1Pathway:TACI and BCMA stimulation of B cell immune responses.0.2970.217181161115188922
parson_gbmh_41bbPathway:The 4-1BB-dependent immune response0.2970.217181161115188922
parson_gbmh_cytokinePathway:Cytokine Network0.2970.217181161115188922
parson_gbmh_barr-mapkPathway:Role of ?-arrestins in the activation and targeting of MAP kinases0.3080.227191161115198921
parson_gbmh_etsPathway:METS affect on Macrophage Differentiation0.3190.237201161115208920
parson_gbmh_cdk5Pathway:Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway0.3380.257221161115228918
parson_gbmh_ngfPathway:Nerve growth factor pathway (NGF)0.3380.257221161115228918
parson_gbmh_dcPathway:Dendritic cells in regulating TH1 and TH2 Development0.3380.257221161115228918
parson_gbmh_cdMacPathway:Cadmium induces DNA synthesis and proliferation in macrophages0.3490.266231161115238917
parson_gbmh_mPRPathway:How Progesterone Initiates the Oocyte Maturation0.3560.276241161115248916
parson_gbmh_inflamPathway:Cytokines and Inflammatory Response0.3560.276241161115248916
parson_gbmh_cellcyclePathway:Cyclins and Cell Cycle Regulation0.3660.285251161115258915
parson_gbmh_TPOPathway:TPO Signaling Pathway0.3750.294261161115268914
parson_gbmh_mitochondriaPathway:Role of Mitochondria in Apoptotic Signaling0.3820.303271161115278913
parson_gbmh_il6Pathway:IL 6 signaling pathway0.3820.303271161115278913
parson_gbmh_ceramidePathway:Ceramide Signaling Pathway0.4010.321291161115298911
parson_gbmh_bArrestin-srcPathway:Roles of ?-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling0.410.33301161115308910
parson_gbmh_tgfbPathway:TGF beta signaling pathway0.4490.364341161115348906
parson_gbmh_deathPathway:Induction of apoptosis through DR3 and DR4/5 Death Receptors 0.4530.372351161115358905
parson_gbmh_fMLPpathway:fMLP induced chemokine gene expression in HMC-1 cells0.4530.372351161115358905
parson_gbmh_malPathway:Role of MAL in Rho-Mediated Activation of SRF0.460.38361161115368904
parson_gbmh_p38mapkPathway:p38 MAPK Signaling Pathway 0.5130.426421161115428898
parson_gbmh_erk5Pathway:Role of Erk5 in Neuronal Survival11261160116268914
parson_gbmh_Ccr5Pathway:Pertussis toxin-insensitive CCR5 Signaling in Macrophage11121160116128928
parson_gbmh_thelperPathway:T Helper Cell Surface Molecules11121160116128928
parson_gbmh_setPathway:Granzyme A mediated Apoptosis Pathway11121160116128928
parson_gbmh_hsp27Pathway:Stress Induction of HSP Regulation11131160116138927
parson_gbmh_rabPathway:Rab GTPases Mark Targets In The Endocytotic Machinery11141160116148926
parson_gbmh_eif2Pathway:Regulation of eIF211111160116118929
parson_gbmh_tcytotoxicPathway:T Cytotoxic Cell Surface Molecules11141160116148926
parson_gbmh_wntPathway:WNT Signaling Pathway11271160116278913
parson_gbmh_reckPathway:Inhibition of Matrix Metalloproteinases11141160116148926
parson_gbmh_calcineurinPathway:Effects of calcineurin in Keratinocyte Differentiation11111160116118929
parson_gbmh_bcellsurvivalPathway:B Cell Survival Pathway11131160116138927
parson_gbmh_sppaPathway:Aspirin Blocks Signaling Pathway Involved in Platelet Activation11271160116278913
parson_gbmh_tcapoptosisPathway:HIV Induced T Cell Apoptosis11101160116108930
parson_gbmh_actinYPathway:Y branching of actin filaments11111160116118929
parson_gbmh_ctlPathway:CTL mediated immune response against target cells 11141160116148926
parson_gbmh_no2il12Pathway:NO2-dependent IL 12 Pathway in NK cells11111160116118929
parson_gbmh_stathminPathway:Stathmin and breast cancer resistance to antimicrotubule agents11121160116128928
parson_gbmh_akap95Pathway:AKAP95 role in mitosis and chromosome dynamics119116011698931
parson_gbmh_shhPathway:Sonic Hedgehog (Shh) Pathway11101160116108930
parson_gbmh_CCR3Pathway:CCR3 signaling in Eosinophils11311160116318909
parson_gbmh_tob1Pathway:Role of Tob in T-cell activation11151160116158925
parson_gbmh_granulocytesPathway:Adhesion and Diapedesis of Granulocytes11131160116138927
parson_gbmh_nktPathway:Selective expression of chemokine receptors during T-cell polarization11271160116278913
parson_gbmh_tcraPathway:Lck and Fyn tyrosine kinases in initiation of TCR Activation11131160116138927
parson_gbmh_IL12Pathway:IL12 and Stat4 Dependent Signaling Pathway in Th1 Development11211160116218919
parson_gbmh_gcrPathway:Corticosteroids and cardioprotection11141160116148926
parson_gbmh_bbcellPathway:Bystander B Cell Activation119116011698931
parson_gbmh_blymphocytePathway:B Lymphocyte Cell Surface Molecules11111160116118929
parson_gbmh_asbcellPathway:Antigen Dependent B Cell Activation11131160116138927
parson_gbmh_mhcPathway:Antigen Processing and Presentation117116011678933
parson_gbmh_th1th2Pathway:Th1/Th2 Differentiation11211160116218919
parson_gbmh_il5Pathway:IL 5 Signaling Pathway11111160116118929